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The product, which received FDA approval in March 2023, was approved based on data from the randomized, double-blind, placebo-controlled phase 3 LAVENDER study (ClinicalTrials. A calibrated measuring device (eg, oral syringe, oral dosing cup) should be obtained from the pharmacy to measure and deliver the prescribed dose accurately. Rett syndrome in adult and pediatric patients 2 years of age and older. Findings showed that treatment with trofinetide led to statistically significant improvements on the Rett Syndrome Behaviour Questionnaire total score mirapex and alcohol and the Clinical Global Impression-Improvement score at week 12 compared with placebo (coprimary endpoints).

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